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Information provided for the test includes types of specimens required, volume and handling instructions. If you are unable to locate the test you need please call our Client Services Department at 1-800-877-7016.

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CREATG      Creatinine
Reported as: CREATININE
Also known as: CREAT, GFR, eGFR
  
Specimen Requirements
 
Collect:  One gold gel 3.5 mL (also acceptable: plain red )
(FOR HOSPITALS ONLY: also acceptable one green Lithium Heparin gel, 3.0 mL)

Note: If the patient is to be given N-Acetylcysteine (NAC) venipuncture should be performed prior to NAC administration to avoid falsely decreased results. NAC is typically used to treat acetaminophen overdose.
 
Transport:   1.0 mL (min: 0.5 mL) serum or plasma refrigerated
Separate serum/plasma from cells ASAP.
 
Stability:  Ambient: 24 Hours serum or plasma / Refrigerated: 7 Days serum (plasma refrigerated: 3 days) / Frozen: 14 Days serum or plasma
  
Ordering Instructions
 
Order Remarks:  Refer to test code CREAFL (Creatinine, Body Fluid) for Creatinine testing on any other sample source besides blood.
  
Test Performance
 
Performed:  Daily
 
Reporting Time:  Final within 24 Hours
  
CPT Codes
 
82565
  
Interpretive Information
 
The estimated GFR (eGFR) is reported in two categories: African American and non-African American. Reporting is as follows:

eGFR results <91 are reported as a numeric value, mL/min/1.73m²


The interpretive guidelines for numeric values are as follows:

eGFR greater than or equal to 90 = Stage 1, normal kidney function.

eGFR 60 - 89 = Stage 2 CKD (chronic kidney disease), or mild kidney disease.

eGFR 30 - 59 = Stage 3 CKD (chronic kidney disease), or moderate kidney disease.

eGFR 15 - 29 = Stage 4 CKD (chronic kidney disease), or severe kidney disease.

eGFR <15 = Stage 5 CKD (chronic kidney disease), or kidney failure.


The CKD-EPI (National Kidney Foundation Chronic Kidney Disease - Epidemiology) equation is used for this estimation. The eGFR is invalid if the serum creatinine is changing on a daily basis, as in dialysis patients or patients with acute renal failure. The CKD-EPI equation has not been validated in patients >93 years of age and the clinician must determine suitability of the value for the patient.


If the patient is <18 years of age, or age/sex of the patient is unknown, a statement is reported that reads, "GFR NOT CALCULATED FOR AGE LESS THAN 18 YEARS ."

N- Acetylcysteine (NAC) may cause falsely decreased triglyceride results. NAC is typically used in treatment of Acetaminophen overdose.
  
Components
 
Creatinine (CREA)Estimated GFR African American (GFRA)
Estimated GFR Non-African American (GFRNA) 
  
Revision History
 
EffectiveTypeRevision
04/21/2016OtherAdded new note in Collect and Interpretive information as requested in DB 10364 by Chem TATm.
10/25/2015Interpretive InfoUpdated specimen requirements and interpretive information as requested in DB 6513 of the October 2015 build cycle.

The information on this page is current as of 07/30/2016.
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